Izabela Przybyłek and Tomasz M. Karpinski *
Department of Medical Microbiology, Poznan´ University of Medical Sciences, Wieniawskiego 3, 61-712 Poznan, Poland; firstname.lastname@example.org
* Correspondence: email@example.com or firstname.lastname@example.org; Tel.: +48-61-854-61-38
Academic Editor: Juraj Majtan
Researchers are continuing to discover all the properties of propolis due to its complex composition and associated broad spectrum of activities. This review aims to characterize the latest scientiﬁc reports in the ﬁeld of antibacterial activity of this substance. The results of studies on the
inﬂuence of propolis on more than 600 bacterial strains were analyzed. The greater activity of propolis against Gram-positive bacteria than Gram-negative was conﬁrmed. Moreover, the antimicrobial activity of propolis from diﬀerent regions of the world was compared. As a result, high activity of propolis from the Middle East was found in relation to both, Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) strains. Simultaneously, the lowest activity was demonstrated for propolis samples from Germany, Ireland and Korea.
propolis; bee product; antibacterial; Staphylococcus aureus; Escherichia coli; polyphenols; terpenoids