Petruta Violeta Filip1,2, Denisa Cuciureanu¹, Laura Sorina Diaconu1,2, Ana Maria Vladareanu1,2, Corina Silvia Pop1
1. “Carol Davila” University of Medicine and Pharmacy, Bucharest
2. Department of Internal Medicine II and Gastroenterology, Emergency University Hospital, Bucharest
Primary gastric lymphoma (PGL) represents a rare pathology, which can be easily misdiagnosed because of unspecific symptoms
of the digestive tract. Histologically, PGL can vary from indolent marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) to aggressive diffuse large B-cell lymphoma (DLBCL). During the years, clinical trials revealed the important role of Helicobacter pylori (H. pylori) in the pathogenesis of gastric MALT lymphoma. Infection with Helicobacter pylori is an influential promoter of gastric lymphomagenesis initiation. Long-term studies revealed that eradication therapy could regress gastric lymphomas.
Keywords: gastric lymphoma, Helicobacter pylori, mucosa-associated lymphoid tissue lymphoma, diffuse large B-cell lymphoma